Acneiform Dermatosis: Adverse Effect to Topical Androgenetic Alopecia Treatment in a Woman

Sanchez DV and Coutino GM

Published on: 2022-04-25


Introduction: many topical treatments for androgenetic alopecia are available, as it is the most common cause of non-scarring alopecia. However, few information is available regarding its side effects.

Case presentation: We present the case of a 45-year-old female that received topical treatment with biotin, melatonin and Ginko Biloba for incipient androgenetic alopecia, commercialized as Lambdapil™ and she developed an acneiform dermatosis in the face as well as seborrhea. This is the first report of a side effect related to this combination as far as we could find.

Conclusion: Biotin has been used for acne and seborrhea treatment, however, as a paradox, it has been reported to because acne flares as it hinders the absorption of vitamin B5 in the intestine.