Hypersensitivity to Ha Dermal Fillers Following Sars-Cov-2 Vaccination

Majewska L

Published on: 2021-12-31


The author presents two cases of hypersensitivity to HA fillers which appeared 24-48 hours after SARS-CoV-2 mRNA vaccination. Modifications in HA filler manufacturing processes in recent years make them more resistant to enzymatic degradation. HA fillers may persist in the tissues for even up to few years thus increasing a risk of hypersensitivity reaction when a trigger factor (such as infection, dental treatment or others) appears. Two treatment methods were successfully used and described in this report. Further knowledge of the cutaneous manifestations and hypersensitivity reactions to HA fillers following SARS-CoV-2 vaccination may help in early diagnosis and treatment.