Diagnostic Utility of ASL And APT-CEST MRI In the Differential Diagnosis of Papillary Glioneuronal Tumor: A Case Report

Harsith L, Kamye S and Kouraki L

Published on: 2023-04-17

Abstract

Papillary glioneuronal tumor (PGNT) is a low-grade biphasic tumor that is composed of glial fibrillary acidic protein (GFAP)-positive glial cells and synaptophysin-positive neurons. We report a case of PGNT occurring in the right occipital lobe of a 48-year-old woman who presented with the symptom of acute headache and left homonymous hemianopsia, which was difficult to distinguish from malignant brain tumors because of peritumoral brain edema, intratumoral hemorrhage, and intraoperative fluorescence staining. PGNT should be included as one of the differential diagnoses in case that the tumor shows hemorrhagic change despite decreased perfusion in ASL-MRI and moderate signal intensity increase in APT-CEST MRI.