Remarkable Response of Vildagliptin/Metformin (EquMet) for Diabetic Patient with Recovered Ratio of Eicosapentaenoic Acid/ Arachidonic Acid (EPA/AA) by EPA Intake

Bando M, Tanaka N, Imamura Y, Yoneda S, Yamada K, Yuasa M and Bando H

Published on: 2023-06-30


The case was 70-year-old male with type 2 diabetes (T2D), dyslipidemia and bilateral internal carotid artery plaques. The eicosapentaenoic acid/ Arachidonic acid (EPA/AA) ratio was 0.21 in September 2019. By administration of ethyl icosapentate, EPA/AA was increased to 0.44 in October 2020. For echogram of carotid artery, bilateral plaque was observed, and the size of the bulbus Φ (right/left) was 2.41/2.48 mm in 2018, and 2.65/2.72 mm in 2020, respectively. For T2D, combined agents of vildagliptin/Metformin (EquMet) brought HbA1c reduction from 6.9% to 6.3% for 2 months, indicating remarkable clinical effect.