Unchanged Arterial Stiffness for Long in Diabetic Patient with Low LDL/HDL Ratio Treated by Equmet (Vildagliptin/Metformin) And Twymeeg (Imeglimin)

Bando H, Iwatsuki N, Okada M, Ogawa T and Sakamoto K

Published on: 2023-09-01

Abstract

This case is 76-year-old female patient with T2D and hypertension for 12 years. HbA1c increased to 7.7% in January 2022, and decreased to 7.0% by vildagliptin/metformin (EquMet) for 9 months. However, it increased to 7.5% in Jan 2023 again. Providing imeglimin (Twymeeg) showed effect for reduction to 6.7% for 4 months. Her lipid profile showed HDL 94 mg/dL, LDL 69 mg/dL, TG 30 mg/dL, T-Cho 169 mg/dL with remarkable low arterial stiffness index (ASI) 0.8. For plethysmography, cardio-ankle vascular index (CAVI) showed stable for 10 years. These two factors are likely close-related to each other, preventing exacerbating arteriosclerosis.