The former head nurse who passed away at the age of 80 was a patient who was in good health and visited the outpatient clinic once a month until her death.In January 1982, 33 years ago, she underwent laparotomy for sigmoid colon cancer, and the gross findings were P1, H0, S3, N2(+), Stage IV, so the surgery was judged to be non-cura B. However, high anterior resection was performed (pathology was papillotubular adenocarcinoma).In September of the same year, removal of metastatic tumor in the right lower abdomen, in February 1983, dissection of metastatic lymph nodes in the left groin and combined resection of the sigmoid colon, in October of the same year, dissection of metastatic lymph nodes in the right groin were performed,?and in April 1984, combined ileocecal colon and mesenteric metastatic lymph node dissection (surgery time 7 hours), in November of the same year, a second right inguinal metastatic lymph node dissection and metastatic partial cystectomy were performed, and in December of the same year, removal of metastatic lymph nodes in the right groin region were performed.?In April 1985, removal of metastatic mesenteric lymph nodes and combined resection of the small intestine (operation time 7 hours) were performed in intestinal obstruction due to metastatic mesenteric lymph nodes. In February 1986, a left groin metastatic lymph node dissection was performed, and in January 1987, intestinal obstruction occurred again due to a mesenteric metastatic lymph node, and combined resection of the mesenteric metastatic lymph node, small intestine and partial metastasis of left diaphragm (operation time 7 hours) were performed. In April 1991, our gynecologist asked me to perform an operation for cervical cancer because we had undergone 10 laparotomy operations, so I underwent my 11th total hysterectomy (operation time 4 hours) under general anesthesia.The patient had undergone cancer removal or lymph node dissection 11 times under general anesthesia, and it was obvious that there was residual cancer in the peritoneum and mesenteric lymph nodes within the abdominal cavity. There was no doubt about the existence of metastasis.

Even before she passed away 28 years later, her tumor markers showed normal values ??and there were no signs of recurrence, so it is no exaggeration to say that this was a case of spontaneous recovery from cancer.

Looking back at what kind of anticancer drugs and immunostimulatory preparations were administered to this case after surgery, we found that anticancer drugs such as Doxifluridine capsules were orally administered in small amounts. As an immunostimulatory preparation, we used 6g of LEM every day for several years, which was heat-extracted from fermented shiitake mycelium components, which is an acronym for Lentinus Edodes, the scientific name of shiitake mushroom and Mycelia. Also we were done clinical trials on rats?with LEM at the time.

In particular, it may be a blessing that the patient was not given strong anticancer drugs.

In this way, the long-term administration of LEM, which is heat-extracted from fermented shiitake mushroom mycelium and whose main components are water-soluble lignin, five-monosaccharide arabinose, and xylol, activated the natural healing mechanism. I have no choice but to believe so [1-3].

The patient we remember had colorectal cancer and we performed surgery on the cancer and its metastatic tumor under general anesthesia 11 times, but we were no able to remove all the recurrent cancer or dissect the metastatic lymph nodes. There was a patient who was so healthy that it was hard to wonder where the cancer had gone after 28 years, despite the fact that she definitely had cancer. The reality is that it is evidence.

In particular, the fact that the intake of non-absorbable dietary fiber such as LEM plays an important role in preventing cancer metastasis suggests that the current nutritional management methods that provide guidance on eating foods that good for digestion after surgery may have the opposite effect. There are concerns that this may be increasing the number of metastasis.

I believe that the natural recovery of cancer may be further enhanced by dietary guidance, but one of the mechanisms of natural cancer recovery for patients who definitely have residual cancer after surgery is the intake of dietary fiber immediately after surgery. I would like to emphasize that this is important.

There are problems with the academic system that focuses only on what is absorbed when it comes to nutrition, but if cancer metastasis can be prevented by consuming dietary fiber, then it is believed that a diet containing dietary fiber will play a major role in cancer treatment. I would like all those involved to be convinced. We need to wake up, and I think we should also reflect on modern medicine, which relies only on drugs.

1. Suzuki Y, Tazawa K, Yamashita I, Sawadaishi M, Kasagi  T, Nagase T, et al. Antitumor effect of water-soluble fraction prepared from culture medium of Lentinus edodes mycelia, on colonic tumors induced by azoxymethane in rats. J Japan Society Coloproctology. 1990; 43: 178-191.
2. Sugano N, Hibino Y, Choji Y, Maeda H. Anticarcinogenic actions of water-soluble and alcohol-insoluble fractions from culture?medium of Lentinus edodes mycelia. Cancer Letters. 1982; 17: 109-114.
3. Morinaga H, Tazawa K, Tagoh H, Muraguchi A, Fujimaki M. An in vivo study of hepatic and splenic interleukin-1β mRNA expression following oral PSK or LEM administration. Japanese J Cancer Res. 1994; 85: 1298-1303.