Long term follow up of Wolcott Rallison Syndrome
Pandya J, Agrawal P, Bhade K, Agrawal A, Gupta N and Bajoria P
Published on: 2023-09-08
Abstract
Neonatal Diabetes Mellitus is a rare genetic condition with an approximate incidence of 1 in 90000 - 160,000 live births [1]. The usual age of presentation is within 6 months and rarely from 6 to 12 months [1]. It may require treatment with insulin therapy, transiently or permanently. The two main pathogenic mechanisms are altered development and survival of beta cells due to pancreatic malformation or due to abnormal functioning of beta cells. Common genetic mutations ABCC8 or KCNJ11 genes are an important cause of neonatal diabetes [1].