Cefepime - Induced Encephalopathy: A Case Report from Vietnam

Nguyen TLA and Le TTQ

Published on: 2025-12-23

Abstract

Cefepime, a fourth-generation cephalosporin, is a renally excreted antibiotic widely used for severe infections. Though Cefepime-induced encephalopathy is a rare side effect, its incidence is increasing due to higher antibiotic use and growing drug resistance. While decreased glomerular filtration rate is a well-known risk factor, recent studies have shown that a significant number of patients with normal renal function can also develop this serious side effect.

This case report emphasizes the importance of closely monitoring mental status changes in all patients treated with Cefepime, regardless of their renal function.