Is It Really In Your Genes? The Case for DNA Dependent Long Term Memory Storage

Stuebs J

Published on: 2019-10-24


In the past century, studies on memory have made considerable advances in elucidating the mechanisms by which memory is stored. One of the most prominent explanations of long term memory storage is the theory of synaptic connectivity. However, it still remains unclear how synaptic connectivity is capable of storing memory engrams for up to a lifetime. The current review discusses alternative, DNA dependent mechanisms of memory storage and explains how epigenetic mechanisms of memory storage, namely DNA methylation and histone acetylation may be capable of encoding and storing memory in a more stable, long term fashion than synaptic connectivity alone.