The Impact of Biofilms in Alzheimer’s disease compared to Other Diseases in Which They Play a Role

Allen HB, Cusack CA and Joshi SG

Published on: 2019-12-26

Abstract

Herein we present the findings related to biofilms in Alzheimer’s disease and compare them to known findings related to biofilms in other chronic diseases. Similarities include microbes making the biofilms both intra and extracellularly, the interaction of the innate immune system in many instances, the devastating impact of the adaptive immune system, and the devastating impact resulting from the various genes involved. Differences include location, the production of beta amyloid, neurofibrillary tangles, and hyperphosphorylated tau protein. The diseases compared include atopic dermatitis, psoriasis, tinea versicolor, leprosy, gout, rheumatoid arthritis and other arthritides.