International Journal of Stem Cells and Regenerative Medicine (IJSCRM) aims to publish high quality papers in all major areas of stem cell biology. We encourage the submission of manuscripts that meet the general criteria of significance and scientific excellence.
We therefore invite you to send Research, Review, Case reports, Editorials, Opinions, Short communications, Mini review, Analysis, case studies, Reports, Image Articles, Perspective and Commentary for the current and the forthcoming issues of International Journal of Stem Cells and Regenerative Medicine.
In biology, regeneration is the process of renewal, restoration, and growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans.
Stem cells are undifferentiated cells, that can differentiate into specialized cells and can divide to produce more stem cells. They are found in multicellular organisms. In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells'ectoderm, endoderm, and mesoderm - but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.
Tissue Repair and Regeneration
Tissue repair and regeneration following injury or disease are often thought to recapitulate embryonic development by using similar molecular and cellular pathways. In addition, many embryonic tissues, such as the spinal cord, heart, and limbs, have some regenerative potential and may utilize mechanisms that can be exogenously activated in adult tissues.
Rejuvenation is a medical discipline focused on the practical reversal of the aging process. Rejuvenation is distinct from life extension. Life extension strategies often study the causes of aging and try to oppose those causes in order to slow aging. Rejuvenation is the reversal of aging and thus requires a different strategy, namely repair of the damage that is associated with aging or replacement of damaged tissue with new tissue. Rejuvenation can be a means of life extension, but most life extension strategies do not involve rejuvenation.
Tissue engineering is emerging as a significant potential alternative or complementary solution, whereby tissue and organ failure is addressed by implanting natural, synthetic, or semisynthetic tissue and organ mimics that are fully functional from the start, or that grow into the required functionality.
Cell and Organ Regeneration
Some parts of our bodies can repair themselves quite well after injury, but others don't repair at all. We certainly can't regrow a whole leg or arm, but some animals Can regrow - or regenerate - whole body parts. Regeneration means the regrowth of a damaged or missing organ part from the remaining tissue. As adults, humans can regenerate some organs, such as the liver.
Translational science is a multidisciplinary form of science that bridges the recalcitrant gaps that sometimes exist between fundamental science and applied science, necessitating something in between to translate knowledge into applications. The term is most often used in the health sciences and refers to the translation of bench science, conducted only in a lab, to bedside clinical practice or dissemination to population-based community interventions.
Models of Regeneration
Discovered centuries ago, regeneration is a fascinating biological phenomenon that continues to intrigue. The study of regeneration promises to inform how adult tissues heal and rebuild themselves such that this process may someday be stimulated in a clinical setting.
Stem Cell Treatments
Regenerative medicine is an emerging branch of medicine with the goal of restoring organ and/or tissue function for patients with serious injuries or chronic disease in which the bodies own responses are not sufficient enough to restore functional tissue. New and current Regenerative Medicines can use stem cells to create a living and functional tissues to regenerate and repair tissue and organs in the body that are damaged due to age, disease, and congenital defects. Stem cells have the power to go to these damaged areas and regenerate new cells and tissues by performing a repair and a renewal process, restoring functionality. Regenerative medicine has the potential to provide a cure for failing or impaired tissues.
Cellular therapy, also called live cell therapy, cellular suspensions, glandular therapy, fresh cell therapy, sicca cell therapy, embryonic cell therapy, and organotherapy - refers to various procedures in which processed tissue from animal embryos, fetuses or organs, is injected or taken orally. Products are obtained from specific organs or tissues said to correspond with the unhealthy organs or tissues of the recipient.
Gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery. Gene therapy is currently only being tested for the treatment of diseases that have no other cures.
Immunotherapy, also called biologic therapy, is a type of cancer treatment designed to boost the body's natural defense to fight cancer. It uses materials either made by the body or in a laboratory to improve, target, or restore immune system function.
Stem Cell Transplantation
Stem cell transplantation is a procedure that is most often recommended as a treatment option for people with leukemia, multiple myeloma, and some types of lymphoma. It may also be used to treat some genetic diseases that involve the blood. During a stem cell transplant, diseased bone marrow (the spongy, fatty tissue found inside larger bones) is destroyed with chemotherapy and/or radiation therapy and then replaced with highly specialized stem cells that develop into the healthy bone marrow. Although this procedure used to be referred to as a bone marrow transplant, today it is more commonly called a stem cell transplant because it is stem cells in the blood that are typically being transplanted, not the actual bone marrow tissue.
International Journal of Stem Cells and Regenerative Medicine also features in the form of Research article, Original, Editorial, Review, short communication, Case report, Letter to the editor, Commentary, book review, etc.,
Area: Stem Cells and Regenerative Medicine
Review Process: Double blinded peer review process
Publication Timeline: 15 Days peer review process
The articles submitted by authors must contain a minimum of 80% unique content (Which should be unique and must not copy from any other web sites). The authors must maintain 100% uniqueness in the Results and conclusion part of the text. We will resend the articles, which have below 80% uniqueness to the authors for revision and asked for resubmissions with uniqueness (as per guidelines).
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International Journal of Stem Cells and Regenerative Medicine (IJSCRM) is a journal that circulates articles based on the global development of stem cell biology. The mission of IJSCRM to publish in a timely manner all stem cell biology specialties comprising a comprehensive resource for physicians around the World.
The following classifications and topics related to it will be considered for publication in the International Journal of Stem Cells and Regenerative Medicineh but, not limited to the following fields