Cell Therapy of Parkinson’s disease with Modified Neural Stem Cells: Explore the Possibilities

Chakraborty A and Diwan A

Published on: 1970-01-01

Abstract

Parkinson’s disease (PD) is characterized by movement disorders, slow speech, and many 21other additional non-motor function disabilities. PD results when a neurotransmitter in the substantia nigra (SN). There is currently no cure for PD available, only management options with DOPA supplementation. However, long-term use of DOPA therapies may result in significant adverse effects, like dyskinesia or motor neuron defects. A number of exciting treatment possibilities may result in near future. One of them is the regenerative cell therapy of PD. However, the main limitation is the availability of sufficient amounts of dopaminergic neuronal cells. Here, we discuss the possible modification method to generate sufficient, functional DOPA-producing cells for regenerative cell therapy of PD.