Changes in Enzyme Activities in the Plasma of Tilapia guineensis Exposed to Glyphosate in the Laboratory

Okenwa U, Eze BU, Nwosu P and Ogolo C

Published on: 2024-07-26

Abstract

Changes in the activity of enzymes are useful markers of stress brought on by any toxin that fish have been exposed to. Decreases in intestinal microflora activity and immunological responses may be the outcome of their activity disturbances. The present study examined the effects of various glyphosate concentrations (0.00, 0.50, 1.00, 1.50, and 2.00 mg/l) on the activities of enzymes in the plasma of Tilapia guineensis exposed for a period of 15 days, including aspartate transaminase (AST), alanine transaminase (ALT), acid phosphatase (ACP), alkaline phosphates (ALP), and lactate dehydrogenase (LDH). The analysis of the enzyme study's results showed that every enzyme significantly (P <0.05) exceeded the control values. The juvenile fish exposed to the alteration had a greater degree of severity than the adult fish, depending on the concentration. In conclusion, changes in plasma enzyme parameters can be used as rapid and reliable indicators of monitoring toward the effects of toxicants on aquatic organisms and ultimately the ecosystem as a whole. These parameters may be attributed to target tissue damage and dysfunction brought on by toxicants.