Beneficial Influence of Pre-Prandial Whey Protein Intake on Stable Glucose Variability

Bando H, Urasaki H and Bando M

Published on: 2025-10-02

Abstract

Pre-prandial whey protein would be beneficial as recent development on continuous glucose monitoring (CGM). Carbohydrate intake always bring post-prandial hyperglycemia (PPH) for diabetic patients. Pre-prandial ingestion of milk, yogurt or whey protein can decrease PPH with satisfactory degree. Whey protein increased insulin secretion, produced an incretin effect, delayed gastric emptying, and regulated appetite. From RCT data, Whey protein group showed significantly lower blood glucose at 60min as -2.67 mmol/l (-48.1 mg/dL), and at 120min as -1.59 mmol/L (-28.6 mg/dL) than placebo group. Whey Protein Microgel (WPM) 10g showed clinical efficacy for reducing PPH and increasing insulin, BCAAs and GLP-1.