Durable Response Using Bio-Enhanced Nanosuspension of Curcumin in Metastatic Colorectal Cancer: A Case Report

Khamar B

Published on: 2020-03-15

Abstract

Colorectal cancer with hepatic metastasis is known for recurrence following curative surgery. Elderly female had left hemi colectomy for colorectal cancer with synchronous hepatic metastasis in July 2013. Histopathology revealed moderately differentiated adenocarcinoma of sigmoid colon infiltrating outermost layer of muscular is layer with focal invasion of fat, pathological stage IV. She was not willing for adjuvant/palliative chemotherapy following surgery and had 50 mg of Nano suspension of cur cumin with improved bioavailability twice a day. This was well tolerated and resulted in durable partial response lasting till date (more than 5 years).