The Role of Berberine Against Hepatocellular Carcinoma

Lu Y, Han DG and Liu W

Published on: 2023-10-05

Abstract

Hepatocellular carcinoma is one of the digestive tract malignant tumors, which has high incidence rate and high mortality. As a traditional Chinese medicine, berberine is commonly used in the treatment of infectious enteritis. In recent years, a large number of studies have shown that berberine can prevent and treat hepatocellular carcinoma, the specific mechanism of which may be related to induction of apoptosis and autophagic cell death, inhibition of proliferation, blocking invasion and metastasis, as well as antioxidant stress and so on. This paper reviews the research progress of berberine in the prevention and treatment of hepatocellular carcinoma.