Variations of Liver Enzymes in Coptodon guineensis Exposed to Butachlor

Ayaobu-Cookey IK, Akinrotimi OA, Orokotan OO and Ogbuzuru-Ebe LS

Published on: 2025-06-18

Abstract

Living organisms exposed to toxicants may exhibit changes in their liver enzymes, which include transaminase, phosphatase, and dehydrogenase activities, which are useful markers of stress. Using the plasma of Coptodon guineensis exposed to butachlor for 15 days, this study examined the effects of varying butachlor concentrations (0.00 mg/l-control 0.05, 0.10, 0.15, and 0.20 mg/l) on the activities of phosphatase, dehydrogenase, and transaminases, including lactate dehydrogenase (LDH), acid phosphatase (ACP), lactate transaminase (ALT), and aspartate transaminase (AST). The enzyme testing findings showed that all of the enzymes were significantly elevated compared to the control values (P < 0.05). Compared to the adult fish, the juvenile fish subjected to the alteration showed a greater degree of severity, depending on the concentration. In conclusion, changes in plasma enzyme parameters can be used as rapid and precise indicators to monitor the effects of toxicants on aquatic life and, ultimately, the habitat overall. These elements might have something to do with the way toxicants produce tissue damage and malfunction.