An Overview on Brain Tumors and Epilepsy

Khoshnevisan A

Published on: 2021-07-25


Seizures are frequent in patients with brain tumors, and patient quality of life can be influenced significantly by epilepsy.  Between all tumor types, seizures are mainly observed with glioneuronal tumors (70–80%), particularly in cases with front temporal or insular location. Besides, seizures are commonly seen in patients with glioma, and the highest rates of epilepsy (60–75%) are seen in cases with low-grade gliomas situated in superficial cortical or insular area. Additionally seizure is experienced in nearly 20–50% of cases with meningioma and 20–35% of patients with brain metastases. Around 60–90% of tumors will be seizure-free following tumor removal, with most favorable results seen in cases with glioneuronal tumors. Gross total resection, earlier surgical therapy, and absence of generalized seizures are main forecaster of a positive seizure outcome. Physicians should not prescribe enzyme-inducing anticonvulsants since simultaneous chemotherapy usually consist a critical part of glioma therapy.