Eyelid Collagenoma: A Case Report

Allison D and Anderson A

Published on: 2024-10-21

Abstract

We present a rare case of an asymptomatic collagenoma of the eyelid. Collagenomas are a type of connective tissue nevus, which are benign dermal hamartomas that form due to either fibroblast proliferation or an overproduction of one or more of the extracellular matrix components (i.e. collagen, elastin, or proteoglycans).

There are several variations of collagenomas that each have important disease and syndromic associations. Therefore, even in an unusual clinical context, pathologists should not overlook this diagnosis if the lesion shows appropriate histomorphology and immunohistochemical staining. Additionally, the diagnosis of collagenoma should prompt clinicians to assess the need for further workup of related diseases and syndromes.