Approach to Disorders in Liver Function Tests in Children

Engin MMN

Published on: 2019-09-10

Abstract

Liver function tests include alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), prothrombin time (PT), INR (International Normalized Ratio), albumin, gamma glutamyl transpeptidase (GGT), alkaline phosphatase (ALP) and bilirubin. Liver function test heights are frequently seen in patient follow-up. It may occur in asymptomatic pediatric patients, metabolic diseases, drug intake, acute and liver diseases. Detailed history and family history are essential in the clinical approach. The age of the patient is important in the differential diagnosis. Accurate evaluation of liver function tests in children is very important, because the correct interpretation of the test and the correct diagnosis is necessary for the diagnosis and follow-up of the patient.