Multi-Drug Resistant Candida Auris Infections in Extreme Low Birth Weight Neonates: A Growing Concern

Bijarniya KM and Kalane S

Published on: 2024-09-27

Abstract

Background: Candida auris is a multidrug-resistant fungus that poses a significant threat to extreme low birth weight (ELBW) neonates, who are already vulnerable due to their immature immune systems.

Aim: To study the risk factors, clinical presentation, treatment and outcome of C. auris infections in ELBW neonates.

Methods: A retrospective cohort study of 5 ELBW neonates who developed C. Auris infection in a tertiary care neonatal intensive care unit over 1 years.

Results: The mean birth weight and gestational age was 645±85gms and 27 ± 2 weeks respectively. ELBW neonates are at increased risk of C. auris colonization and infection, which can manifest as sepsis, meningitis, or urinary tract infections. Accurate diagnosis requires advanced laboratory testing, and treatment options are limited due to antifungal resistance.

Conclusion: C. auris infections in ELBW neonates require prompt recognition, effective treatment, and stringent infection control measures to prevent transmission.