Lipases in the Enantioselective Biocatalysis Process to Obtain Enantiomerically Pure Racemic Products

Schuenck-Rodrigues RA

Published on: 2022-05-28

Abstract

Obtaining enantiomerically pure substances is of great industrial interest, since enantiomers can present differences in odor, taste, toxicity and, mainly, biological action. From this, several methodologies have been developed for the stereoselective synthesis of organic compounds (asymmetric synthesis), among which biocatalysis using lipases as biocatalysts stands out, as they present a versatility of method and applications. The present study aimed to present the different applications and productions of racemic products and the use of enzymes as biocatalysts by enantioselectivity process to obtain enantiomerically pure compounds. From the study, it was possible to observe that lipases are important biocatalysts in industrial processes and are becoming an important tool for advances in biotechnology. It was possible to conclude that the lipases show promise in the process of purification of racemic products in order to obtain enantiomerically pure substances, as they present selectivity in the presence of specific substrates in order to solve challenging chiral substrate problems.