Novel Method for Estimation of Thymol in Pharmaceutical Preparation and Spiked Industrial Wastewater Sample

Ahmed NR, Al-Etewi MJE and Hussein AA

Published on: 2023-10-10

Abstract

A novel simple, rapid and sensitive method for the determination of thymol in smicks ointment using p-aminophenol has been developed. The reaction is carried out in aqueous alkaline solution [KOH] and p-aminophenol to yield a color compound shows maximum absorbance at 600 nm against blank. Beer^? s law was obeyed in the concentration range of 2-28µg/ml. The molar absorptivity and Sandell^?s sensitivity of the colored complex are 0.75x10⁴ l/mol.cm. And 20.04 ng/cm² respectively. RSD less than1.0% and accuracy was 100.06 .The method was applied successfully for assay of thymol in smicks ointment and environmental water sample.